INT354218

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.74
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Accn1) extracellular space (Igfbp7) extracellular region (Igfbp7)
cell adhesion (Igfbp7) plasma membrane (Accn1)
Igfbp7 (Mus musculus)
Accn1 (Mus musculus)
Pain Link Frequency Relevance Heat
ASIC 30 96.72 Very High Very High Very High
IPN 14 75.56 Quite High
Inflammation 34 75.00 Quite High
Pain 26 58.16 Quite High
agonist 4 51.92 Quite High
Nerve growth factor 8 5.00 Very Low Very Low Very Low
ischemia 8 5.00 Very Low Very Low Very Low
Neuronal excitability 6 5.00 Very Low Very Low Very Low
sodium channel 4 5.00 Very Low Very Low Very Low
Serotonin 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aids-related Complex 16 99.84 Very High Very High Very High
Acidosis 28 89.20 High High
Inflammatory Pain 14 75.56 Quite High
INFLAMMATION 38 75.00 Quite High
Pain 24 58.16 Quite High
Injury 6 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Coronary Artery Disease 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to the homomeric ASIC3 channels, AGM also activated heteromeric ASIC3 plus ASIC1b channels, extending its potential physiological relevance.
AGM Positive_regulation (activated) of ASIC1b
1) Confidence 0.04 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC3017031 Disease Relevance 0.45 Pain Relevance 0.24
Similar to GMQ [10], none of the homomeric channels ASIC1a, ASIC1b, or ASIC2a were activated by either AGM or ARC (Figure 7A, C).
AGM Positive_regulation (activated) of ASIC1b associated with aids-related complex
2) Confidence 0.03 Published 2010 Journal Mol Pain Section Body Doc Link PMC3017031 Disease Relevance 0.29 Pain Relevance 0.21

General Comments

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