INT354224

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Accn3) extracellular region (Bdnf) plasma membrane (Accn3)
cytoplasmic membrane-bounded vesicle (Bdnf) cytoplasm (Accn3)
Anatomy Link Frequency
brain 2
Bdnf (Mus musculus)
Accn3 (Mus musculus)
Pain Link Frequency Relevance Heat
bradykinin 1 99.88 Very High Very High Very High
Serotonin 2 99.20 Very High Very High Very High
Nerve growth factor 4 98.96 Very High Very High Very High
Pain 13 98.60 Very High Very High Very High
Inflammatory mediators 1 98.28 Very High Very High Very High
nociceptor 1 91.16 High High
IPN 7 89.60 High High
ischemia 4 87.28 High High
Inflammation 17 86.44 High High
PcTx1 2 82.28 Quite High
Disease Link Frequency Relevance Heat
Pain 12 98.60 Very High Very High Very High
INFLAMMATION 19 98.08 Very High Very High Very High
Inflammatory Pain 7 89.60 High High
Acidosis 14 89.44 High High
Hematoma 1 87.72 High High
Cv Unclassified Under Development 2 87.28 High High
Infection 3 86.88 High High
Coronary Artery Disease 2 48.96 Quite Low
Myalgia 1 41.52 Quite Low
Aids-related Complex 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, inflammatory mediators, such as nerve growth factor (NGF), serotonin (5-HT), interleukin-1, bradykinin, and brain-derived neurotrophic factor (BDNF) can stimulate ASIC3 transcription, which perhaps contributes to the pain-enhancing effects of these mediators [49,50].
brain-derived neurotrophic factor Positive_regulation (stimulate) of Transcription (transcription) of ASIC3 in brain associated with pain, inflammatory mediators, nerve growth factor, bradykinin and serotonin
1) Confidence 0.09 Published 2010 Journal Mol Pain Section Body Doc Link PMC3017031 Disease Relevance 1.04 Pain Relevance 0.95

General Comments

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