INT354400

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Context Info
Confidence 0.35
First Reported 2011
Last Reported 2011
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.55
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL18, TNFSF12) extracellular region (IL18, TNFSF12) cell differentiation (TNFSF12)
cell-cell signaling (IL18) cytoplasm (IL18) cytosol (IL18)
IL18 (Homo sapiens)
TNFSF12 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 69 99.32 Very High Very High Very High
Inflammation 24 49.92 Quite Low
alcohol 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 9 89.16 High High
Cancer 9 88.80 High High
Death 12 84.40 Quite High
Apoptosis 15 80.52 Quite High
INFLAMMATION 24 49.92 Quite Low
Reprotox - General 3 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Myeloid Leukemia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TWEAK expression is not regulated by IL-18 and IL-18 has no effect on TWEAK mRNA.
IL-18 Neg (not) Regulation (regulated) of Gene_expression (expression) of TWEAK
1) Confidence 0.35 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3017546 Disease Relevance 0 Pain Relevance 0.04
Stimulation of recombinant protein IL-18 or its antibody in the culture medium did not influence subsequent TWEAK expression if compared to the control condition.
recombinant protein IL-18 Neg (not) Regulation (influence) of Gene_expression (expression) of TWEAK
2) Confidence 0.30 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3017546 Disease Relevance 0 Pain Relevance 0.05
Therefore we investigated whether TWEAK regulates IL-18 expression or at the opposite if IL-18 acts on TWEAK expression.
IL-18 Regulation (acts) of Gene_expression (expression) of TWEAK
3) Confidence 0.21 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3017546 Disease Relevance 0.55 Pain Relevance 0.08

General Comments

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