INT354469

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Context Info
Confidence 0.08
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.82
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (SDHC, Sdhb) mitochondrion (SDHC, Sdhb) oxidoreductase activity (Sdhb)
small molecule metabolic process (SDHC)
SDHC (Homo sapiens)
Sdhb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Catecholamine 6 32.72 Quite Low
imagery 4 28.24 Quite Low
headache 3 5.00 Very Low Very Low Very Low
vincristine 2 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
positron emission tomography 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pheochromocytoma 75 100.00 Very High Very High Very High
Syndrome 10 100.00 Very High Very High Very High
Paraganglioma 3 100.00 Very High Very High Very High
Malignant Neoplastic Disease 28 97.68 Very High Very High Very High
Cancer 16 95.12 Very High Very High Very High
Multiple Endocrine Neoplasia Type 2a 5 94.16 High High
Diabetes Mellitus 5 42.40 Quite Low
Body Weight 1 41.36 Quite Low
Cv Unclassified Under Development 9 40.36 Quite Low
Insulin Resistance 1 33.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently, the succinate dehydrogenase D, B, and C (SDHD, SDHB, SDHC) genes, which are associated with familial pheochromocytoma and/or paraganglioma syndrome, have been identifed.14 Of these six genes, SDHB mutations are associated strongly with extra-adrenal and malignant pheochromocytoma.18-20 Whether or not genetic testing should be performed in all patients with sporadic pheochromocytoma remains controversial.
SDHC Binding (associated) of SDHB associated with malignant neoplastic disease, syndrome, paraganglioma and pheochromocytoma
1) Confidence 0.08 Published 2011 Journal Yonsei Medical Journal Section Body Doc Link PMC3017707 Disease Relevance 1.82 Pain Relevance 0

General Comments

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