INT354535

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Context Info
Confidence 0.15
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Pkd2) transport (Pkd2) endoplasmic reticulum (Pkd2)
plasma membrane (Pkd2) cilium (Pkd2) transmembrane transport (Pkd2)
Anatomy Link Frequency
kidney 2
Pkd2 (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 1 98.44 Very High Very High Very High
antagonist 3 98.08 Very High Very High Very High
Calcium channel 2 26.88 Quite Low
Angina 1 12.56 Low Low
imagery 27 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
TRP channel 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
pain flank 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autosomal Dominant Polycystic Kidney 111 99.36 Very High Very High Very High
Disease 31 97.88 Very High Very High Very High
Cyst 25 93.84 High High
Coronary Heart Disease 4 64.36 Quite High
Polycystic Kidney Disease 12 64.08 Quite High
Left Ventricular Hypertrophy 15 62.20 Quite High
Cv Unclassified Under Development 20 58.08 Quite High
Syndrome 15 50.00 Quite Low
Disease Progression 6 32.24 Quite Low
Proteinuria 3 23.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An antagonist with high potency and selectivity for the human VPV2R (tolvaptan) has also been shown to be an effective treatment in PKD2 mouse model of autosomal dominant polycystic kidney disease [91].
Regulation (effective) of Negative_regulation (treatment) of PKD2 in kidney associated with antagonist, autosomal dominant polycystic kidney, disease and potency
1) Confidence 0.15 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3017903 Disease Relevance 1.03 Pain Relevance 0.14

General Comments

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