INT354677

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Context Info
Confidence 0.51
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.06
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Pick1) protein targeting (Pick1) Golgi apparatus (Pick1)
ATPase activity (Pick1) plasma membrane (Pick1) enzyme binding (Pick1)
Pick1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 4 97.44 Very High Very High Very High
ASIC 22 72.16 Quite High
Glutamate 2 47.84 Quite Low
Kinase C 2 22.96 Low Low
imagery 6 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 64.24 Quite High
Toxicity 12 16.44 Low Low
Acidosis 8 15.56 Low Low
Death 16 8.40 Low Low
Disease 8 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Male Infertility 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PNGase treatment reduced all slower migrating species to the faster migrating species in both control and PICK1 overexpressing conditions.
Negative_regulation (reduced) of Gene_expression (overexpressing) of PICK1
1) Confidence 0.51 Published 2010 Journal Mol Brain Section Body Doc Link PMC3018362 Disease Relevance 0 Pain Relevance 0
In contrast, overexpression of PICK1 decreases surface expression of AMPA receptors [31,33,36,51] and netrin-1 receptor UNC5H1 [52].
Negative_regulation (decreases) of Gene_expression (overexpression) of PICK1
2) Confidence 0.37 Published 2010 Journal Mol Brain Section Body Doc Link PMC3018362 Disease Relevance 0.06 Pain Relevance 0.08

General Comments

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