INT354682

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ASIC1, PKN1) plasma membrane (ASIC1, PKN1) endosome (PKN1)
transport (ASIC1) histone binding (PKN1) nucleus (PKN1)
ASIC1 (Homo sapiens)
PKN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
ASIC 11 88.64 High High
imagery 3 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 96.96 Very High Very High Very High
Toxicity 6 94.40 High High
Death 8 5.00 Very Low Very Low Very Low
Acidosis 4 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Male Infertility 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, ASIC1a interacts with PICK1 (protein interacting with C-kinase 1), an intracellular protein that regulates trafficking of several membrane proteins.
ASIC1a Binding (interacting) of C-kinase 1
1) Confidence 0.01 Published 2010 Journal Mol Brain Section Abstract Doc Link PMC3018362 Disease Relevance 0.19 Pain Relevance 0.04

General Comments

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