INT354697

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Gria2, Pick1) plasma membrane (Gria2, Pick1) mitochondrion (Pick1)
transport (Gria2) Golgi apparatus (Pick1) endoplasmic reticulum (Gria2)
Gria2 (Mus musculus)
Pick1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 1 100.00 Very High Very High Very High
Pain 1 82.80 Quite High
Multiple sclerosis 1 80.60 Quite High
ischemia 1 79.48 Quite High
Central nervous system 1 65.52 Quite High
ASIC 11 62.28 Quite High
imagery 3 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 85.68 High High
Pain 1 82.80 Quite High
Convulsion 1 82.20 Quite High
Demyelinating Disease 1 80.60 Quite High
Male Infertility 1 79.52 Quite High
Cv Unclassified Under Development 1 79.48 Quite High
Neurological Disease 1 78.72 Quite High
Anxiety Disorder 1 75.12 Quite High
Death 8 5.00 Very Low Very Low Very Low
Toxicity 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, interaction of PICK1 with GluR2, an AMPA-type glutamate receptor subunit, is important for synaptic targeting and surface expression of AMPA receptors during synaptic plasticity [26-33].
Positive_regulation (important) of GluR2 Binding (interaction) of PICK1 associated with glutamate receptor
1) Confidence 0.08 Published 2010 Journal Mol Brain Section Body Doc Link PMC3018362 Disease Relevance 0.73 Pain Relevance 0.33

General Comments

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