INT354725

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ASIC1) transport (ASIC1) endoplasmic reticulum (Bfar)
plasma membrane (ASIC1) molecular_function (Bfar)
ASIC1 (Homo sapiens)
Bfar (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 1 10.48 Low Low
ASIC 11 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acidosis 4 42.56 Quite Low
Toxicity 6 40.80 Quite Low
Apoptosis 1 19.68 Low Low
Death 8 18.48 Low Low
Disease 4 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Male Infertility 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To answer the question whether mutating the BAR domain of PICK1 interferes with its interaction with ASIC1a, we performed co-immunoprecipitation analysis.
Spec (whether) Negative_regulation (interferes) of ASIC1a Binding (interaction) of BAR
1) Confidence 0.05 Published 2010 Journal Mol Brain Section Body Doc Link PMC3018362 Disease Relevance 0 Pain Relevance 0

General Comments

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