INT354867

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Context Info
Confidence 0.38
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.72
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Klk13) extracellular space (Klk13) cytoplasm (Klk13)
Anatomy Link Frequency
T cell 4
Klk13 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 42 69.12 Quite High
cytokine 16 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Chronic pancreatitis 8 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Salivary Gland Disease 40 99.08 Very High Very High Very High
Syndrome 154 96.12 Very High Very High Very High
Sialadenitis 16 94.20 High High
Disease 76 80.48 Quite High
INFLAMMATION 44 69.12 Quite High
Disorders Of The Lacrimal System 58 67.28 Quite High
Sprains And Strains 36 60.24 Quite High
Diabetes Mellitus 44 55.88 Quite High
Aging 2 48.52 Quite Low
Dacryocystitis 6 41.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Enhanced expression of kallikrein-13 (Klk-13) has been detected in salivary glands, suggesting that Klk-13 may be a candidate autoantigen in SjS that could contribute to the development of sialadenitis due to increased T cell response to organs expressing Klk-13 [63].

2.6.

Positive_regulation (Enhanced) of Gene_expression (expression) of Klk-13 in T cell associated with syndrome, salivary gland disease and sialadenitis
1) Confidence 0.38 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3018660 Disease Relevance 0.86 Pain Relevance 0.03
Enhanced expression of kallikrein-13 (Klk-13) has been detected in salivary glands, suggesting that Klk-13 may be a candidate autoantigen in SjS that could contribute to the development of sialadenitis due to increased T cell response to organs expressing Klk-13 [63].

2.6.

Positive_regulation (Enhanced) of Gene_expression (expression) of kallikrein-13 in T cell associated with syndrome, salivary gland disease and sialadenitis
2) Confidence 0.27 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3018660 Disease Relevance 0.86 Pain Relevance 0.03

General Comments

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