INT354869

Context Info Confidence 0.42 First Reported 2011 Last Reported 2011 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.72 Pain Relevance 0.07

peptidase activity (Klk13) extracellular space (Klk13) cytoplasm (Klk13)

Anatomy Link Frequency T cell 2 Klk13 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 42 68.76 cytokine 16 5.00 rheumatoid arthritis 10 5.00 Chronic pancreatitis 8 5.00 tolerance 4 5.00 Arthritis 4 5.00 fibrosis 2 5.00 anesthesia 2 5.00 Inflammatory response 2 5.00 Multiple sclerosis 2 5.00

Disease Link Frequency Relevance Heat Salivary Gland Disease 40 99.08 Syndrome 154 96.12 Sialadenitis 16 94.20 Disease 76 80.12 INFLAMMATION 44 68.76 Disorders Of The Lacrimal System 58 66.92 Sprains And Strains 36 59.88 Diabetes Mellitus 44 55.52 Aging 2 48.16 Dacryocystitis 6 41.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Enhanced expression of kallikrein-13 (Klk-13) has been detected in salivary glands, suggesting that Klk-13 may be a candidate autoantigen in SjS that could contribute to the development of sialadenitis due to increased T cell response to organs expressing Klk-13 [63]. 2.6.

Gene_expression (expression) of kallikrein-13 in T cell associated with syndrome, salivary gland disease and sialadenitis

1) Confidence 0.42 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3018660 Disease Relevance 0.86 Pain Relevance 0.03

Enhanced expression of kallikrein-13 (Klk-13) has been detected in salivary glands, suggesting that Klk-13 may be a candidate autoantigen in SjS that could contribute to the development of sialadenitis due to increased T cell response to organs expressing Klk-13 [63]. 2.6.

Gene_expression (expression) of Klk-13 in T cell associated with syndrome, salivary gland disease and sialadenitis

2) Confidence 0.42 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3018660 Disease Relevance 0.86 Pain Relevance 0.03

General Comments

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