INT354896

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Context Info
Confidence 0.04
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Psen2, Fancd2) Golgi apparatus (Psen2) endoplasmic reticulum (Psen2)
embryo development (Psen2) protein complex (Psen2) cytosol (Psen2)
Anatomy Link Frequency
brains 1
Psen2 (Mus musculus)
Fancd2 (Mus musculus)
Psen2 - N141I (1)
Pain Link Frequency Relevance Heat
Inflammatory response 2 61.08 Quite High
Inflammation 1 39.60 Quite Low
positron emission tomography 1 38.80 Quite Low
imagery 2 34.40 Quite Low
Inflammatory mediators 1 31.88 Quite Low
Hippocampus 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 33 100.00 Very High Very High Very High
Cognitive Disorder 11 88.28 High High
Alzheimer's Dementia 22 87.00 High High
Targeted Disruption 13 73.16 Quite High
INFLAMMATION 4 60.72 Quite High
Amyloid Plaque 11 22.88 Low Low
Body Weight 2 5.00 Very Low Very Low Very Low
Amyloidosis 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
40 in the brains of the PS2Tg2576 mice at 4-5 months of age were consistent with the values observed in a human FAD patient with the PS2 (N141I) mutation (Table 1).
PS2 (N141I) Binding (patient) of FAD in brains associated with disease
1) Confidence 0.04 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3018662 Disease Relevance 0.75 Pain Relevance 0.03

General Comments

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