INT35502

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Context Info
Confidence 0.57
First Reported 1984
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 0.18
Pain Relevance 2.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrh) extracellular region (Ghrh) plasma membrane (Gnrhr)
signal transducer activity (Gnrhr)
Anatomy Link Frequency
Pituitary 2
anterior pituitary 2
Ghrh (Rattus norvegicus)
Gnrhr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opiate 8 100.00 Very High Very High Very High
Opioid 4 100.00 Very High Very High Very High
Intracerebroventricular 2 98.66 Very High Very High Very High
tetrodotoxin 3 96.40 Very High Very High Very High
Morphine 5 93.48 High High
Enkephalin 1 80.16 Quite High
Clonidine 7 79.20 Quite High
sodium channel 1 75.00 Quite High
Somatostatin 4 50.08 Quite High
noradrenaline 4 25.00 Low Low
Disease Link Frequency Relevance Heat
Immunization 2 99.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Growth-hormone releasing factor (GRF) induces feeding and growth hormone (GH) release.
GRF Positive_regulation (induces) of Localization (release) of growth hormone
1) Confidence 0.57 Published 1997 Journal Peptides Section Abstract Doc Link 9149291 Disease Relevance 0 Pain Relevance 0.47
Growth-hormone releasing factor (GRF) induces feeding and growth hormone (GH) release.
Growth-hormone releasing factor Positive_regulation (induces) of Localization (release) of growth hormone
2) Confidence 0.57 Published 1997 Journal Peptides Section Abstract Doc Link 9149291 Disease Relevance 0 Pain Relevance 0.47
The effects of intracerebroventricular (i.c.v.) or intracarotid (i.a.) administration of amylin (AMY) on growth hormone (GH) release induced by GH-releasing hormone (GHRH) were examined in conscious male rats.
GHRH Positive_regulation (induced) of Localization (release) of growth hormone associated with intracerebroventricular
3) Confidence 0.34 Published 1995 Journal Neuroendocrinology Section Abstract Doc Link 8538870 Disease Relevance 0 Pain Relevance 0.07
The effects of intracerebroventricular (i.c.v.) or intracarotid (i.a.) administration of amylin (AMY) on growth hormone (GH) release induced by GH-releasing hormone (GHRH) were examined in conscious male rats.
GH-releasing hormone Positive_regulation (induced) of Localization (release) of growth hormone associated with intracerebroventricular
4) Confidence 0.34 Published 1995 Journal Neuroendocrinology Section Abstract Doc Link 8538870 Disease Relevance 0 Pain Relevance 0.05
Pituitary secretion of growth hormone in response to opioid peptides and opiates is mediated through growth hormone-releasing factor.
growth hormone-releasing factor Positive_regulation (mediated) of Localization (secretion) of growth hormone in Pituitary associated with opiate and opioid
5) Confidence 0.32 Published 1985 Journal Neuroendocrinology Section Title Doc Link 3160962 Disease Relevance 0.10 Pain Relevance 0.47
Both pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) and growth hormone-releasing hormone (GRH) stimulated growth hormone (GH) release from perfused rat anterior pituitary cells.
growth hormone-releasing hormone Positive_regulation (stimulated) of Localization (release) of growth hormone in anterior pituitary
6) Confidence 0.24 Published 1998 Journal Regul. Pept. Section Abstract Doc Link 9533816 Disease Relevance 0 Pain Relevance 0.31
Evidence that opiatergic and alpha-adrenergic mechanisms stimulate rat growth hormone release via growth hormone-releasing factor (GRF).
growth hormone-releasing factor Positive_regulation (stimulate) of Localization (release) of growth hormone
7) Confidence 0.13 Published 1984 Journal Endocrinology Section Title Doc Link 6325138 Disease Relevance 0.08 Pain Relevance 0.16

General Comments

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