INT355036

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (CKAP4, TP53) cytoplasm (CKAP4, TP53) cell differentiation (TP53)
nucleoplasm (TP53) mitochondrion (TP53) enzyme binding (TP53)
Anatomy Link Frequency
T24 2
CKAP4 (Homo sapiens)
TP53 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 3 62.56 Quite High
interstitial cystitis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bladder Cancer 32 92.88 High High
Metastasis 3 76.96 Quite High
Cancer 7 73.32 Quite High
Interstitial Cystitis 6 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Carcinoma 2 5.00 Very Low Very Low Very Low
Retinoblastoma 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The current study confirms this result by showing that synthetic as-APF also increases p53 protein and mRNA expression in T24 cells, and it further demonstrates the role of the CKAP4 receptor in APF-induced p53 upregulation.
CKAP4 receptor Regulation (role) of Positive_regulation (upregulation) of p53 in T24
1) Confidence 0.08 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC3020166 Disease Relevance 0.40 Pain Relevance 0.03

General Comments

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