INT355218

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.34
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Tjp1) plasma membrane (Tjp1) nucleus (Tjp1)
cytoplasm (Tjp1)
Tjp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 10 73.12 Quite High
Intracerebroventricular 2 58.40 Quite High
Central nervous system 8 17.72 Low Low
imagery 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 4 83.44 Quite High
Brain Hemorrhage 4 74.32 Quite High
Targeted Disruption 2 54.32 Quite High
Cv General 4 Under Development 4 37.28 Quite Low
Hypoxia 6 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 6 5.00 Very Low Very Low Very Low
Brain Injury 6 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Brain Tumor 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data provides evidence that focused ultrasound in the presence of circulating ultrasound contrast agents (microbubbles) disrupts the interaction of tight junction proteins (occludin and ZO-1), thus affecting the integrity of the BBB.
Regulation (affecting) of ZO-1 Binding (interaction) of
1) Confidence 0.18 Published 2010 Journal BMC Neurol Section Body Doc Link PMC3020671 Disease Relevance 0.27 Pain Relevance 0.06
It has been shown that the post-translational modifications play an essential role in controlling the interaction of occludin and ZO-1.
Regulation (controlling) of ZO-1 Binding (interaction) of
2) Confidence 0.18 Published 2010 Journal BMC Neurol Section Body Doc Link PMC3020671 Disease Relevance 0.07 Pain Relevance 0.04

General Comments

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