INT355244

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Context Info
Confidence 0.04
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 2.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cacna1a) DNA binding (Cacna1a) transmembrane transport (Cacna1a)
cytoplasm (Cacna1a) cell death (Cacna1a) nucleus (Cacna1a)
Cacna1a (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 252 100.00 Very High Very High Very High
qutenza 158 100.00 Very High Very High Very High
long-term potentiation 148 100.00 Very High Very High Very High
antagonist 36 99.08 Very High Very High Very High
GABAergic 18 91.76 High High
Hippocampus 12 71.12 Quite High
gABA 10 65.84 Quite High
Neurotransmitter 4 49.36 Quite Low
Substantia gelatinosa neuron 2 37.44 Quite Low
Action potential 2 37.04 Quite Low
Disease Link Frequency Relevance Heat
Depression 6 16.16 Low Low
Epilepsy 2 15.80 Low Low
Anxiety Disorder 14 5.00 Very Low Very Low Very Low
Pain 10 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The capsaicin-induced reduction of LA-LTP could be also blocked by the specific TRPV1 antagonist AMG9810 (1 µM cap: 110.4±5.5% [n?
Negative_regulation (blocked) of Negative_regulation (reduction) of LA associated with qutenza, antagonist, long-term potentiation and amygdala
1) Confidence 0.04 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020947 Disease Relevance 0 Pain Relevance 1.78
This co-application also did not block the suppressive action of capsaicin on LA-LTP (SR: 130.2±6.0% [n?
Negative_regulation (block) of Negative_regulation (suppressive) of LA associated with qutenza, long-term potentiation and amygdala
2) Confidence 0.04 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020947 Disease Relevance 0 Pain Relevance 0.89

General Comments

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