INT355261

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Context Info
Confidence 0.31
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 5.37
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Saa3)
Anatomy Link Frequency
lungs 2
neutrophils 1
Saa3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 48 89.92 High High
chemokine 30 80.00 Quite High
cytokine 36 8.96 Low Low
Pain 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 15 100.00 Very High Very High Very High
Mycobacterial Infection 435 99.40 Very High Very High Very High
INFLAMMATION 48 89.92 High High
Infection 330 89.24 High High
Injury 3 88.80 High High
Granuloma 15 5.00 Very Low Very Low Very Low
Shock 12 5.00 Very Low Very Low Very Low
Necrosis 9 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Strikingly, we found significant induction of transcripts encoding Serum amyloid protein 3 (SAA3) in the D12 M.tuberculosis-infected lungs (Table 7).
Positive_regulation (induction) of SAA3 in lungs associated with mycobacterial infection and alzheimer's dementia
1) Confidence 0.31 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020951 Disease Relevance 1.87 Pain Relevance 0.08
Strikingly, we found significant induction of transcripts encoding Serum amyloid protein 3 (SAA3) in the D12 M.tuberculosis-infected lungs (Table 7).
Positive_regulation (induction) of Serum amyloid protein 3 in lungs associated with mycobacterial infection and alzheimer's dementia
2) Confidence 0.21 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020951 Disease Relevance 1.86 Pain Relevance 0.08
can induce SAA3 induction [56] and serum amyloid proteins which can in turn mediate priming of neutrophils via induction of reactive oxygen species [57], [58].
Positive_regulation (induction) of SAA3 in neutrophils associated with alzheimer's dementia
3) Confidence 0.21 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020951 Disease Relevance 1.64 Pain Relevance 0.08

General Comments

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