INT35527

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Context Info
Confidence 0.17
First Reported 1988
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.38
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Eef1a2) GTPase activity (Eef1a2) cytoplasm (Eef1a2)
Eef1a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 13 100.00 Very High Very High Very High
Potency 4 82.48 Quite High
Neuropeptide 2 47.28 Quite Low
Opioid 2 44.76 Quite Low
Enkephalin 2 43.68 Quite Low
dexamethasone 11 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Calcification 139 99.60 Very High Very High Very High
Apoptosis 21 5.00 Very Low Very Low Very Low
Atherosclerosis 12 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 3 5.00 Very Low Very Low Very Low
Myocardial Infarction 2 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Osteoporosis 1 5.00 Very Low Very Low Very Low
Chronic Renal Failure 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The data indicate the presence of an extended binding site in the enzyme with residues interacting with S1, S1', and S3' subsites largely determining inhibitor binding.
Regulation (residues) of S1 Binding (interacting) of
1) Confidence 0.17 Published 1988 Journal Biochemistry Section Abstract Doc Link 3162384 Disease Relevance 0 Pain Relevance 0.08
The data indicate the presence of an extended binding site in the enzyme with residues interacting with S1, S1', and S3' subsites largely determining inhibitor binding.
Regulation (residues) of S1 Binding (interacting) of
2) Confidence 0.17 Published 1988 Journal Biochemistry Section Abstract Doc Link 3162384 Disease Relevance 0 Pain Relevance 0.08
Effect of a combination of CA and statin on in vitro VSMC calcification
Regulation (Effect) of statin Binding (combination) of associated with calcification and antagonist
3) Confidence 0.02 Published 2007 Journal Mol Cell Biochem Section Body Doc Link PMC2226060 Disease Relevance 1.38 Pain Relevance 0.05

General Comments

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