INT355333

Context Info Confidence 0.03 First Reported 2011 Last Reported 2011 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.15 Pain Relevance 0

plasma membrane (Bmpr2) kinase activity (Bmpr2) cytoplasm (Bmpr2)

Anatomy Link Frequency PC-3 2 Bmpr2 (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 14 50.00 imagery 6 5.00 cytokine 4 5.00 Pain 4 5.00 analgesia 2 5.00 Spinal cord 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Reprotox - General 1 26 98.36 Cancer 84 50.64 Targeted Disruption 2 29.68 Osteolysis 9 21.92 Metastasis 45 5.00 Osteoporosis 34 5.00 Hypercalcemia 23 5.00 Multiple Myeloma 10 5.00 Pain 4 5.00 Spontaneous Fractures 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The mRNA expression of BMP-2,-3,-6 and -7 was not modified in both Nog-KD clones as compared to parental PC-3, while BMP-4 mRNA was undetectable in both parental and Nog-KD cells (not shown).

Neg (not) Regulation (modified) of Transcription (expression) of BMP-2 in PC-3

1) Confidence 0.03 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020964 Disease Relevance 0.15 Pain Relevance 0

General Comments

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