INT355584

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Context Info
Confidence 0.06
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.35
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA) growth (VEGFA) extracellular region (VEGFA)
cell adhesion (CDH5) proteinaceous extracellular matrix (VEGFA) plasma membrane (CDH5)
VEGFA (Homo sapiens)
CDH5 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 2 91.60 High High
cytokine 2 86.52 High High
Central nervous system 9 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
methotrexate 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
intrathecal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 42 100.00 Very High Very High Very High
Adhesions 11 100.00 Very High Very High Very High
Metastasis 76 76.56 Quite High
Cancer 82 74.68 Quite High
Hypoxia 1 44.24 Quite Low
Brain Tumor 9 35.80 Quite Low
Disease 6 5.00 Very Low Very Low Very Low
Vomiting 5 5.00 Very Low Very Low Very Low
Headache 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also showed that VEGF secreted from breast cancer cells significantly increased the adhesion and penetration of breast cancer cells across the HBMECs monolayer, via changes of VE-cadherin which were inhibited by SU-1498 inhibitor for VEGFR-2 and calcium chelator.
VEGF Positive_regulation (increased) of Positive_regulation (changes) of VE-cadherin associated with breast cancer and adhesions
1) Confidence 0.06 Published 2011 Journal Pathology Research International Section Body Doc Link PMC3021881 Disease Relevance 1.35 Pain Relevance 0.09

General Comments

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