INT355587

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Context Info
Confidence 0.01
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (TJP1) plasma membrane (TJP1) nucleus (TJP1)
cytoplasm (TJP1)
Anatomy Link Frequency
filaments 3
occludin (Homo sapiens)
TJP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 3 9.52 Low Low
bradykinin 3 8.84 Low Low
Inflammatory mediators 3 7.64 Low Low
Central nervous system 27 5.00 Very Low Very Low Very Low
imagery 15 5.00 Very Low Very Low Very Low
headache 12 5.00 Very Low Very Low Very Low
methotrexate 9 5.00 Very Low Very Low Very Low
corticosteroid 6 5.00 Very Low Very Low Very Low
medulla 6 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 33 74.92 Quite High
Metastasis 228 67.92 Quite High
Brain Tumor 27 64.48 Quite High
Breast Cancer 126 57.60 Quite High
Cancer 246 43.84 Quite Low
Brain Injury 6 17.36 Low Low
INFLAMMATION 3 7.24 Low Low
Pressure And Volume Under Development 3 6.68 Low Low
Disease 18 5.00 Very Low Very Low Very Low
Vomiting 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ZO-1 binds to actin filaments and to the C-terminus of occludin and claudins, which couples the structural and dynamic properties of perijunctional actin to the paracellular barrier.
occludin Binding (binds) of ZO-1 in filaments
1) Confidence 0.01 Published 2011 Journal Pathology Research International Section Body Doc Link PMC3021881 Disease Relevance 0.37 Pain Relevance 0
ZO-1 binds to actin filaments and to the C-terminus of occludin and claudins, which couples the structural and dynamic properties of perijunctional actin to the paracellular barrier.
occludin Binding (binds) of ZO-1 in filaments
2) Confidence 0.01 Published 2011 Journal Pathology Research International Section Body Doc Link PMC3021881 Disease Relevance 0.37 Pain Relevance 0
ZO-1 binds to actin filaments and to the C-terminus of occludin and claudins, which couples the structural and dynamic properties of perijunctional actin to the paracellular barrier.
occludin Binding (binds) of ZO-1 in filaments
3) Confidence 0.01 Published 2011 Journal Pathology Research International Section Body Doc Link PMC3021881 Disease Relevance 0.37 Pain Relevance 0

General Comments

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