INT355681

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Context Info
Confidence 0.33
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.00
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl2) extracellular region (Ccl2) cytoskeleton organization (Ccl2)
cytoplasm (Ccl2)
Anatomy Link Frequency
monocyte 4
Ccl2 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 10 100.00 Very High Very High Very High
Inflammation 74 89.64 High High
Arthritis 6 25.44 Quite Low
cytokine 20 14.40 Low Low
ischemia 2 11.60 Low Low
agonist 8 6.80 Low Low
Inflammatory marker 8 5.00 Very Low Very Low Very Low
Inflammatory stimuli 8 5.00 Very Low Very Low Very Low
melanocortin 1 receptor 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 22 99.76 Very High Very High Very High
INFLAMMATION 90 89.64 High High
Coronary Artery Disease 2 48.24 Quite Low
Diabetes Mellitus 6 47.16 Quite Low
Disease 6 46.12 Quite Low
Vasculitis 2 28.16 Quite Low
Arthritis 8 25.44 Quite Low
Adhesions 4 16.48 Low Low
Cv Unclassified Under Development 2 11.60 Low Low
Reperfusion Injury 2 10.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, MC3R KO mice exhibit increased adiposity and nutrient partitioning in addition to impaired immune function, evidenced by decreased macrophage infiltration and decreased monocyte chemoattractant protein 1 (MCP-1) and chemokine of differentiation 68 (CD68) mRNA expression into adipose tissue in comparison to wild-type mice [16, 32].
Negative_regulation (decreased) of Transcription (expression) of monocyte chemoattractant protein 1 in monocyte associated with chemokine and obesity
1) Confidence 0.33 Published 2011 Journal Journal of Aging Research Section Body Doc Link PMC3022199 Disease Relevance 0.50 Pain Relevance 0.21
For example, MC3R KO mice exhibit increased adiposity and nutrient partitioning in addition to impaired immune function, evidenced by decreased macrophage infiltration and decreased monocyte chemoattractant protein 1 (MCP-1) and chemokine of differentiation 68 (CD68) mRNA expression into adipose tissue in comparison to wild-type mice [16, 32].
Negative_regulation (decreased) of Transcription (expression) of MCP-1 in monocyte associated with chemokine and obesity
2) Confidence 0.33 Published 2011 Journal Journal of Aging Research Section Body Doc Link PMC3022199 Disease Relevance 0.50 Pain Relevance 0.21

General Comments

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