INT355714

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf) cytoplasmic membrane-bounded vesicle (Bdnf)
Anatomy Link Frequency
brain 2
Bdnf (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 84 99.84 Very High Very High Very High
Eae 2 75.88 Quite High
Desipramine 3 74.32 Quite High
Hippocampus 7 72.76 Quite High
depression 21 60.32 Quite High
fluoxetine 6 59.76 Quite High
Endep 1 23.12 Low Low
tricyclic antidepressant 1 21.76 Low Low
monoamine 5 5.00 Very Low Very Low Very Low
Serotonin 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 5 84.60 Quite High
Targeted Disruption 5 82.64 Quite High
Depression 59 60.32 Quite High
Anxiety Disorder 5 55.20 Quite High
Manic Depressive Disorder 6 25.16 Quite Low
Frailty 2 5.00 Very Low Very Low Very Low
Affective Disorder 2 5.00 Very Low Very Low Very Low
Hypoactive Sexual Desire Disorder 1 5.00 Very Low Very Low Very Low
Obsessive-compulsive Disorder 1 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, animal studies have shown that an increase in brain BDNF plays an important role in antidepressant action and that the antidepressant response is attenuated in mutant mice with BDNF deficit.
Regulation (role) of Positive_regulation (increase) of BDNF in brain associated with antidepressant
1) Confidence 0.39 Published 2010 Journal Psychiatry Investigation Section Body Doc Link PMC3022309 Disease Relevance 0.34 Pain Relevance 0.73

General Comments

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