INT355723

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (Hist2h4) biological_process (Hist2h4)
Hist2h4 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 20 87.04 High High
long-term potentiation 3 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 64 97.64 Very High Very High Very High
Anxiety Disorder 24 97.20 Very High Very High Very High
Post-traumatic Stress Disorder 9 5.00 Very Low Very Low Very Low
Convulsion 4 5.00 Very Low Very Low Very Low
Mental Disorders 4 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Coma 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results of the fear conditioning study showed that footshock stress significantly increased the levels of total, exon I, and exon IV BDNF mRNA, with significantly increased acetylation levels of both histone H3 and H4, at the promoter of exons I and IV, followed by enhanced freezing to fear-context exposure.
Transcription (levels) of H4 associated with stress and anxiety disorder
1) Confidence 0.02 Published 2010 Journal Psychiatry Investigation Section Abstract Doc Link PMC3022311 Disease Relevance 0.72 Pain Relevance 0.08

General Comments

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