INT355750

Context Info Confidence 0.49 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0

small molecule metabolic process (CYP4F3) endoplasmic reticulum (CYP4F3)

CYP4F3 (Homo sapiens)

Pain Link Frequency Relevance Heat tolerance 12 16.72 Inflammation 4 5.00 Pain 4 5.00

Disease Link Frequency Relevance Heat Pain 4 5.00 INFLAMMATION 4 5.00 Acid Reflux 2 5.00 Sprains And Strains 2 5.00 Poisoning 2 5.00 Burns 2 5.00 Cicatrix 2 5.00 Starvation 2 5.00 Injury 2 5.00 Increased Venous Pressure Under Development 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

For example, the human CYP4F3 gene has two inducer-specific 5' UTR transcriptional start sites capable of controlling the mutually exclusive splicing of either exon 3 or 4, generating the tissue-specific expression of catalytically distinct CYP4F3A and CYP4F3B isoforms [74].

Positive_regulation (inducer) of Gene_expression (expression) of CYP4F

1) Confidence 0.49 Published 2010 Journal BMC Ecol Section Body Doc Link PMC3022543 Disease Relevance 0 Pain Relevance 0

For example, the human CYP4F3 gene has two inducer-specific 5' UTR transcriptional start sites capable of controlling the mutually exclusive splicing of either exon 3 or 4, generating the tissue-specific expression of catalytically distinct CYP4F3A and CYP4F3B isoforms [74].

Positive_regulation (inducer) of Gene_expression (expression) of CYP4F3A

2) Confidence 0.16 Published 2010 Journal BMC Ecol Section Body Doc Link PMC3022543 Disease Relevance 0 Pain Relevance 0

General Comments

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