INT355826

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (BACE1) peptidase activity (BACE1) Golgi apparatus (BACE1)
endoplasmic reticulum (BACE1) enzyme binding (BACE1)
Anatomy Link Frequency
cleavage 2
BACE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 99 99.60 Very High Very High Very High
Nav1.1 4 95.76 Very High Very High Very High
imagery 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Disease Progression 1 5.00 Very Low Very Low Very Low
Brain Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our previous studies, we have found that elevated BACE1-mediated cleavage of human Nav?
Positive_regulation (elevated) of Localization (cleavage) of BACE1 in cleavage associated with sodium channel
1) Confidence 0.43 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC3022600 Disease Relevance 0 Pain Relevance 0.62

General Comments

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