INT355866

Context Info Confidence 0.04 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 3 Disease Relevance 3.56 Pain Relevance 0

transport (Afp) transferase activity, transferring glycosyl groups (EXT1) Golgi apparatus (EXT1) endoplasmic reticulum (EXT1) cytoplasm (Afp) signal transduction (EXT1)

EXT1 (Homo sapiens) Afp (Rattus norvegicus)

Pain Link Frequency Relevance Heat imagery 6 5.00 palliative 3 5.00

Disease Link Frequency Relevance Heat Hepatocellular Cancer 120 100.00 Cancer 234 99.12 Cirrhosis 21 98.84 Liver Disease 39 98.60 Immunotherapy Of Cancer 3 68.80 Infection 12 43.88 Hepatitis C Virus Infection 12 43.48 Hepatitis B Virus Infection 9 41.64 Pressure And Volume Under Development 15 28.16 Recurrence 3 26.32

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Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

To determine the association between TTV and other important prognostic indicators of HCC, the relationship of TTV and serum AFP level, vascular invasion, CTP and MELD score was investigated (Figure 1).

TTV Binding (association) of AFP associated with liver disease and hepatocellular cancer

1) Confidence 0.04 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC3022616 Disease Relevance 1.06 Pain Relevance 0

TTV was also closely linked with serum AFP level and the presence of vascular invasion.

TTV Binding (linked) of AFP

2) Confidence 0.04 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC3022616 Disease Relevance 1.28 Pain Relevance 0

Since TTV can be used to reflect the status of tumor burden, it is not surprising that a larger TTV is expected to be more often associated with a higher AFP level and vascular invasion.

TTV Binding (associated) of AFP associated with cancer

3) Confidence 0.04 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC3022616 Disease Relevance 1.22 Pain Relevance 0

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