INT355905

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.90
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 2
MIR10B (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 20 99.72 Very High Very High Very High
Hepatocellular Cancer 196 99.08 Very High Very High Very High
Cancer 164 97.24 Very High Very High Very High
Liver Cancer 52 95.60 Very High Very High Very High
Metastasis 12 78.56 Quite High
Advanced Or Metastatic Breast Cancer 4 71.68 Quite High
Chromosome Aberrations 4 70.24 Quite High
Chromosomal Instability 4 58.32 Quite High
Colon Cancer 4 48.24 Quite Low
Breast Cancer 8 18.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we validated significant overexpression of miR-10b, miR-21, and miR-34c-3p in SP fractions of HCC compared to SP fractions of normal fetal liver cells.
Gene_expression (overexpression) of miR-10b in liver associated with hepatocellular cancer
1) Confidence 0.02 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC3022676 Disease Relevance 1.37 Pain Relevance 0
As shown in Figure 4A, the results showed that the expression levels of miR-21, miR-34c-3p, miR-16, miR-10b, and let-7i* in SP of HCC cells compared to SP of fetal liver cells were increased 3.5 ± 0.84, 2.1 ± 0.52, 2.2 ± 0.46, 3.9 ± 0.61, and 2.8 ± 0.25 -fold respectively, which were consistent with miRNA microarray results (P < 0.05). of the down-regulated miR-200a*, and miR-148b* in SP of HCC cells had the fold changes 0.1 ± 0.04, and 0.4 ± 0.08, respectively (P < 0.01).
Gene_expression (expression) of miR-10b in liver associated with hepatocellular cancer
2) Confidence 0.02 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC3022676 Disease Relevance 0.54 Pain Relevance 0
By performing real-time PCR, Sasayama et al. [29] found that miR-10b expression was upregulated in gliomas and that the expression of miR-10b was associated with higher-grade glioma.
Gene_expression (expression) of miR-10b associated with glioma
3) Confidence 0.02 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC3022676 Disease Relevance 1.47 Pain Relevance 0
By performing real-time PCR, Sasayama et al. [29] found that miR-10b expression was upregulated in gliomas and that the expression of miR-10b was associated with higher-grade glioma.
Gene_expression (expression) of miR-10b associated with glioma
4) Confidence 0.02 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC3022676 Disease Relevance 1.52 Pain Relevance 0

General Comments

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