INT355906

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (MAPK1, IL8) nucleoplasm (MAPK1) mitochondrion (MAPK1)
DNA binding (MAPK1) microtubule organizing center (MAPK1) extracellular space (IL8)
Anatomy Link Frequency
epithelial cells 2
MAPK1 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 3 97.86 Very High Very High Very High
Inflammation 5 47.60 Quite Low
cytokine 3 46.56 Quite Low
chemokine 5 5.00 Very Low Very Low Very Low
colic 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 8 97.66 Very High Very High Very High
Death 17 87.76 High High
Infection 19 82.84 Quite High
Vibrio Infection 1 59.36 Quite High
Sprains And Strains 26 58.76 Quite High
Gastroenteritis 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Vomiting 2 5.00 Very Low Very Low Very Low
Abdominal Cramps 1 5.00 Very Low Very Low Very Low
Diarrhoea 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, the inflammatory responses induced by the TTSS effectors of Salmonella typhimurium are related to activation of all MAPK, especially p38 which induces IL-8 secretion from epithelial cells [39], and Burkholderia pseudomallei utilizes its TTSS to induce IL-8 secretion and to increase bacterial internalization via activation of p38 and JNK in epithelial cells [44].
p38 Positive_regulation (induces) of Localization (secretion) of IL-8 in epithelial cells associated with inflammatory response
1) Confidence 0.02 Published 2010 Journal BMC Microbiol Section Body Doc Link PMC3022711 Disease Relevance 0.67 Pain Relevance 0.05

General Comments

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