INT355995

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Context Info
Confidence 0.21
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.00
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Prph)
Anatomy Link Frequency
neurons 2
Prph (Rattus norvegicus)
Pain Link Frequency Relevance Heat
c fibre 2 89.52 High High
unmyelinated 2 89.20 High High
dorsal root ganglion 16 84.80 Quite High
Spinal cord 24 69.92 Quite High
Pain 42 53.12 Quite High
Stimulus evoked pain 14 50.00 Quite Low
withdrawal 32 48.96 Quite Low
allodynia 22 44.32 Quite Low
Thermal hyperalgesia 10 14.16 Low Low
Sciatic nerve 34 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 18 88.24 High High
Injury 104 68.40 Quite High
Pain 54 53.12 Quite High
Neuropathic Pain 60 50.00 Quite Low
Hypersensitivity 16 50.00 Quite Low
Hyperalgesia 14 14.16 Low Low
Nervous System Injury 20 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that compared to the contralateral uninjured side, PSNL induced a large increase in the level of ATF3/NF-200 (Figure 2A) and ATF3/peripherin (Figure 2B) with about 25-30% of NF-200 neurons containing ATF+ nuclei and about 28-34% of peripherin neurons containing ATF+ nuclei in the DRGs ipsilateral to the PSNL (left side).
Positive_regulation (increase) of peripherin in neurons
1) Confidence 0.21 Published 2011 Journal Mol Pain Section Body Doc Link PMC3022745 Disease Relevance 0.50 Pain Relevance 0.37
We found that compared to the contralateral uninjured side, PSNL induced a large increase in the level of ATF3/NF-200 (Figure 2A) and ATF3/peripherin (Figure 2B) with about 25-30% of NF-200 neurons containing ATF+ nuclei and about 28-34% of peripherin neurons containing ATF+ nuclei in the DRGs ipsilateral to the PSNL (left side).
Positive_regulation (induced) of peripherin in neurons
2) Confidence 0.21 Published 2011 Journal Mol Pain Section Body Doc Link PMC3022745 Disease Relevance 0.50 Pain Relevance 0.37

General Comments

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