INT35604

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Context Info
Confidence 0.08
First Reported 1988
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.55
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CELA3B) extracellular region (CELA3B)
Anatomy Link Frequency
fat 1
digestive tract 1
CELA3B (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 1 69.68 Quite High
Central nervous system 1 56.84 Quite High
Multiple sclerosis 1 47.84 Quite Low
carpal tunnel syndrome 3 46.16 Quite Low
imagery 1 42.12 Quite Low
peripheral neuropathy 3 30.64 Quite Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 13 100.00 Very High Very High Very High
Disease 5 95.88 Very High Very High Very High
Pancreatitis 4 92.08 High High
Demyelinating Disease 8 85.76 High High
Neuropathic Pain 6 84.64 Quite High
Exocrine Pancreatic Insufficiency 1 64.48 Quite High
Central Nervous System Disease 1 57.16 Quite High
Hyperglycemia 1 56.80 Quite High
Carpal Tunnel Syndrome 3 46.16 Quite Low
Peripheral Neuropathy 3 30.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using radioimmunoassay, we tested serum elastase 1 (E1), an enzyme secreted only from the pancreas, in 200 subjects as follows: 39 healthy subjects as controls, 56 patients with diseases of the digestive tract, 66 patients with hepatobiliary diseases, and 39 patients with pancreatic diseases.
Localization (secreted) of serum elastase 1 in digestive tract associated with pancreatitis and disease
1) Confidence 0.08 Published 1988 Journal Pancreas Section Abstract Doc Link 3174608 Disease Relevance 0.48 Pain Relevance 0.07
Claims that this deficiency is moderate, nonprogressive, and therefore clinically irrelevant (7) are contradicted by the finding of pathologically high fat excretion in diabetic patients with fecal elastase deficiency (4).
Localization (excretion) of fecal elastase in fat associated with diabetes mellitus
2) Confidence 0.06 Published 2008 Journal Diabetes Care Section Body Doc Link PMC2518335 Disease Relevance 1.07 Pain Relevance 0.03

General Comments

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