INT356087

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Context Info
Confidence 0.17
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (App, Ncstn) plasma membrane (App, Ncstn) peptidase activity (Ncstn)
endoplasmic reticulum (Ncstn) cell adhesion (App) extracellular matrix organization (App)
Anatomy Link Frequency
Notch 1
App (Mus musculus)
Ncstn (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 6 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neuronal excitability 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 38 67.36 Quite High
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 5 5.00 Very Low Very Low Very Low
Syndrome 5 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Amyloid Plaque 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One study showed that the ectodomain of Nicastrin binds to APP and Notch and can recruit them into the ?
APP Binding (binds) of Nicastrin in Notch
1) Confidence 0.17 Published 2011 Journal Mol Brain Section Body Doc Link PMC3022812 Disease Relevance 0.07 Pain Relevance 0

General Comments

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