INT356112

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Context Info
Confidence 0.24
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.29
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (App, Apba1) cell adhesion (App) Golgi apparatus (App)
extracellular matrix organization (App) DNA binding (App) protein complex (Apba1)
App (Mus musculus)
Apba1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuronal excitability 3 61.52 Quite High
long-term potentiation 3 46.84 Quite Low
amygdala 3 13.52 Low Low
Kinase C 18 5.00 Very Low Very Low Very Low
sodium channel 6 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
Nerve growth factor 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
nMDA receptor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 27 62.96 Quite High
Death 9 53.56 Quite High
Drug Induced Neurotoxicity 9 21.80 Low Low
Disease 114 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 15 5.00 Very Low Very Low Very Low
Syndrome 15 5.00 Very Low Very Low Very Low
Congenital Anomalies 12 5.00 Very Low Very Low Very Low
Amyloid Plaque 12 5.00 Very Low Very Low Very Low
Adhesions 9 5.00 Very Low Very Low Very Low
Cognitive Disorder 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, the APP C-terminus has been found to interact with all three mint (X11) family members (mint1, mint2, and mint3) involved in trafficking regulation [163-165].
APP Binding (interact) of mint1
1) Confidence 0.24 Published 2011 Journal Mol Brain Section Body Doc Link PMC3022812 Disease Relevance 0.12 Pain Relevance 0.03
For example, the APP C-terminus has been found to interact with all three mint (X11) family members (mint1, mint2, and mint3) involved in trafficking regulation [163-165].
APP Binding (interact) of mint
2) Confidence 0.21 Published 2011 Journal Mol Brain Section Body Doc Link PMC3022812 Disease Relevance 0.12 Pain Relevance 0.03
APP interaction with mint proteins has been shown to affect APP processing by stabilizing cellular APP, altering both sAPP?
APP Binding (interaction) of mint
3) Confidence 0.18 Published 2011 Journal Mol Brain Section Body Doc Link PMC3022812 Disease Relevance 0.06 Pain Relevance 0.03

General Comments

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