INT356217

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Context Info
Confidence 0.59
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.91
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc32a1)
Anatomy Link Frequency
lung 2
respiratory 1
Slc32a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 15 99.72 Very High Very High Very High
Spinal cord 48 96.88 Very High Very High Very High
GABAergic 42 76.08 Quite High
gABA 123 50.00 Quite Low
Glutamate 21 5.00 Very Low Very Low Very Low
Neurotransmitter 18 5.00 Very Low Very Low Very Low
monoamine 12 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 6 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Respiratory Failure 9 99.70 Very High Very High Very High
Atelectasis 3 89.40 High High
Cleft Palate 48 88.32 High High
Umbilical Hernia 72 86.96 High High
Congenital Anomalies 12 85.40 High High
Targeted Disruption 108 50.00 Quite Low
Death 9 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 9 5.00 Very Low Very Low Very Low
Body Weight 9 5.00 Very Low Very Low Very Low
Anxiety Disorder 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, there is still uncertainty regarding the mechanism responsible for the respiratory failure caused by the loss of VGAT protein.
Negative_regulation (loss) of VGAT protein in respiratory associated with respiratory failure
1) Confidence 0.59 Published 2010 Journal Mol Brain Section Body Doc Link PMC3023674 Disease Relevance 0.51 Pain Relevance 0
The alterations in the VGAT-/- muscle, liver and lung were likely caused by the loss of VGAT in the CNS, but not the loss of VGAT in the peripheral tissue because VGAT transcripts were detected in brain and spinal cord, but not in muscle, liver or lung [2,3].


Negative_regulation (loss) of VGAT in lung associated with central nervous system and spinal cord
2) Confidence 0.51 Published 2010 Journal Mol Brain Section Body Doc Link PMC3023674 Disease Relevance 0.73 Pain Relevance 0.14
The alterations in the VGAT-/- muscle, liver and lung were likely caused by the loss of VGAT in the CNS, but not the loss of VGAT in the peripheral tissue because VGAT transcripts were detected in brain and spinal cord, but not in muscle, liver or lung [2,3].


Negative_regulation (loss) of VGAT in lung associated with central nervous system and spinal cord
3) Confidence 0.38 Published 2010 Journal Mol Brain Section Body Doc Link PMC3023674 Disease Relevance 0.67 Pain Relevance 0.13

General Comments

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