INT356228

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Slc18a3)
Anatomy Link Frequency
brains 2
Slc18a3 (Mus musculus)
Pain Link Frequency Relevance Heat
monoamine 8 98.70 Very High Very High Very High
Neurotransmitter 12 91.84 High High
gABA 82 90.32 High High
Glutamate 14 88.88 High High
Spinal cord 32 25.60 Quite Low
GABAergic 28 5.00 Very Low Very Low Very Low
Central nervous system 10 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 72 99.92 Very High Very High Very High
Respiratory Failure 6 86.00 High High
Death 6 59.96 Quite High
Umbilical Hernia 48 53.28 Quite High
Cleft Palate 32 52.16 Quite High
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 6 5.00 Very Low Very Low Very Low
Body Weight 6 5.00 Very Low Very Low Very Low
Anxiety Disorder 6 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, monoamines are drastically reduced in vesicular monoamine transporter 2 knockout brains [15], but acetylcholine (ACh) is increased in vesicular acetylcholine transporter (VAChT) knockout brains compared to control wild-type brains [16].
Positive_regulation (increased) of acetylcholine transporter in brains associated with targeted disruption and monoamine
1) Confidence 0.35 Published 2010 Journal Mol Brain Section Body Doc Link PMC3023674 Disease Relevance 0.45 Pain Relevance 0.47
For example, monoamines are drastically reduced in vesicular monoamine transporter 2 knockout brains [15], but acetylcholine (ACh) is increased in vesicular acetylcholine transporter (VAChT) knockout brains compared to control wild-type brains [16].
Positive_regulation (increased) of VAChT in brains associated with targeted disruption and monoamine
2) Confidence 0.35 Published 2010 Journal Mol Brain Section Body Doc Link PMC3023674 Disease Relevance 0.45 Pain Relevance 0.47

General Comments

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