INT356233

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.60
Pain Relevance 1.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc32a1, Gabrg1) plasma membrane (Gabrg1)
Anatomy Link Frequency
synaptic vesicles 2
Slc32a1 (Mus musculus)
Gabrg1 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 82 100.00 Very High Very High Very High
Glutamate 14 100.00 Very High Very High Very High
Neurotransmitter 12 96.16 Very High Very High Very High
GABAergic 28 94.08 High High
Central nervous system 10 90.76 High High
Pain 2 84.56 Quite High
Spinal cord 32 52.00 Quite High
monoamine 8 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 6 100.00 Very High Very High Very High
Targeted Disruption 72 91.60 High High
Convulsion 2 88.88 High High
Cognitive Disorder 2 88.12 High High
Anxiety Disorder 6 87.36 High High
Pain 2 84.56 Quite High
Cleft Palate 32 81.44 Quite High
Umbilical Hernia 48 38.40 Quite Low
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
Respiratory Failure 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GABA is synthesized from glutamic acid by glutamate decarboxylase (GAD) [1] and is accumulated into synaptic vesicles by the vesicular GABA transporter (VGAT) [2,3].
VGAT Positive_regulation (accumulated) of GABA in synaptic vesicles associated with glutamate, gaba and generalized anxiety disorder
1) Confidence 0.17 Published 2010 Journal Mol Brain Section Body Doc Link PMC3023674 Disease Relevance 0.80 Pain Relevance 0.72
GABA is synthesized from glutamic acid by glutamate decarboxylase (GAD) [1] and is accumulated into synaptic vesicles by the vesicular GABA transporter (VGAT) [2,3].
vesicular GABA transporter Positive_regulation (accumulated) of GABA in synaptic vesicles associated with glutamate, gaba and generalized anxiety disorder
2) Confidence 0.15 Published 2010 Journal Mol Brain Section Body Doc Link PMC3023674 Disease Relevance 0.80 Pain Relevance 0.72

General Comments

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