INT356314

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Context Info
Confidence 0.00
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Crhr1) plasma membrane (Crhr1) molecular_function (ORF61)
cellular_component (ORF61) biological_process (ORF61) response to stress (Crhr1)
Crhr1 (Mus musculus)
ORF61 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 2 90.64 High High
Nucleus accumbens 2 87.92 High High
Neurotransmitter 8 87.12 High High
amygdala 102 86.40 High High
Kinase C 2 77.32 Quite High
gABA 48 67.16 Quite High
GABAergic 32 61.84 Quite High
alcohol 22 42.28 Quite Low
depression 2 41.04 Quite Low
addiction 16 28.08 Quite Low
Disease Link Frequency Relevance Heat
Depression 2 41.04 Quite Low
Alcohol Addiction 16 34.16 Quite Low
Anxiety Disorder 10 28.56 Quite Low
Stress 4 5.00 Very Low Very Low Very Low
Fetal Death 2 5.00 Very Low Very Low Very Low
Recurrence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A switch in coupling from AC9 to AC7 results in a more robust cAMP signal when CRF binds to CRF1 (Antoni, 2000; Antoni et al., 2003).
CRF1 Binding (binds) of AC7
1) Confidence 0.00 Published 2011 Journal Frontiers in Neuroscience Section Body Doc Link PMC3024005 Disease Relevance 0 Pain Relevance 0.30
Antoni et al. (2003) demonstrated a coupling of CRF1 to AC9 and AC7.
CRF1 Binding (coupling) of AC7
2) Confidence 0.00 Published 2011 Journal Frontiers in Neuroscience Section Body Doc Link PMC3024005 Disease Relevance 0 Pain Relevance 0.32

General Comments

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