INT356321

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Context Info
Confidence 0.19
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Crhr1) plasma membrane (Crhr1) response to stress (Crhr1)
signal transducer activity (Crhr1)
Crhr1 (Mus musculus)
Cea (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 51 100.00 Very High Very High Very High
GABAergic 16 97.40 Very High Very High Very High
addiction 8 78.68 Quite High
alcohol 11 78.28 Quite High
tolerance 1 56.88 Quite High
Neurotransmitter 4 54.00 Quite High
gABA 24 48.44 Quite Low
antagonist 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alcohol Addiction 8 85.52 High High
Anxiety Disorder 5 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Fetal Death 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Recurrence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies indicated that in the CeA, ethanol acts through activation of CRF1 and its signaling pathways.
Positive_regulation (activation) of CRF1 Positive_regulation (acts) of CeA associated with amygdala
1) Confidence 0.19 Published 2011 Journal Frontiers in Neuroscience Section Body Doc Link PMC3024005 Disease Relevance 0.37 Pain Relevance 0.56

General Comments

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