INT356329

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Context Info
Confidence 0.09
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Crhr1) plasma membrane (Crhr1) response to stress (Crhr1)
signal transducer activity (Crhr1)
Crhr1 (Mus musculus)
Cea (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 51 100.00 Very High Very High Very High
gABA 24 90.72 High High
GABAergic 16 81.68 Quite High
alcohol 11 73.40 Quite High
withdrawal 2 66.20 Quite High
opiate 1 65.28 Quite High
addiction 8 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 5 99.16 Very High Very High Very High
Recurrence 1 71.56 Quite High
Stress 2 70.56 Quite High
Alcohol Addiction 8 66.20 Quite High
Fetal Death 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our previous and current studies suggest that components of the PKC (Bajo et al., 2008) and PKA signaling pathways are critical for CRF1-mediated effects in the CeA that could underlie anxiety-like and ethanol-related behaviors.
CRF1 Regulation (effects) of CeA associated with anxiety disorder and amygdala
1) Confidence 0.09 Published 2011 Journal Frontiers in Neuroscience Section Body Doc Link PMC3024005 Disease Relevance 0.31 Pain Relevance 0.64

General Comments

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