INT35635

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Context Info
Confidence 0.37
First Reported 1988
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sord) oxidoreductase activity (Sord) cilium (Sord)
cellular_component (Sord)
Anatomy Link Frequency
blood 2
Sord (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 5 99.98 Very High Very High Very High
anesthesia 2 59.32 Quite High
isoflurane 2 58.88 Quite High
Bile 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 6 96.80 Very High Very High Very High
Hepatotoxicity 2 92.92 High High
Aging 1 75.00 Quite High
Hemorrhage 1 50.84 Quite High
Body Weight 18 13.60 Low Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Emaciation 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Dyspepsia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both doses of acetaminophen produced significant elevations of serum alanine aminotransferase (ALT) and sorbitol dehydrogenase (SDH) activities in 4-month-old rats.
Positive_regulation (elevations) of Gene_expression (produced) of sorbitol dehydrogenase associated with paracetamol
1) Confidence 0.37 Published 1988 Journal Drug Chem Toxicol Section Abstract Doc Link 3181038 Disease Relevance 0.24 Pain Relevance 0.42
Clinical biochemistry values analyzed were: serum aspartate aminotransferase, serum alanine aminotransferase, sorbitol dehydrogenase, alkaline phosphatase, total bilirubin, blood urea nitrogen, blood creatinine, total cholesterol, triglycerides, fasting glucose, total serum protein, albumin, globulin, calcium, inorganic phosphorus, sodium, potassium, and chloride.
Positive_regulation (aminotransferase) of Gene_expression (aminotransferase) of sorbitol dehydrogenase in blood associated with disorder of lipid metabolism
2) Confidence 0.15 Published 2009 Journal Nutr J Section Body Doc Link PMC2633017 Disease Relevance 0.15 Pain Relevance 0.17

General Comments

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