INT356366

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.22
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (S1pr1, Gopc) transport (Gopc) signal transduction (S1pr1)
Golgi apparatus (Gopc) cytoplasm (Gopc) signal transducer activity (S1pr1)
Anatomy Link Frequency
lung 2
S1pr1 (Mus musculus)
Gopc (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 38 86.92 High High
anesthesia 2 20.80 Low Low
agonist 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Occupational Lung Diseases 2 96.64 Very High Very High Very High
Asthma 40 93.08 High High
Hypersensitivity 24 92.40 High High
INFLAMMATION 36 86.92 High High
Pneumonia 2 49.04 Quite Low
Exsanguination 2 16.88 Low Low
Disease 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The current study revealed that, although the S1P administration alone had no effect on the lung histology (Fig. 1A, B) and the BAL cell counts in control animals (Fig. 2, Vehicle-Control vs S1P-Control), administration of S1P prior to each antigen challenge aggravated the antigen-induced increase in BAL cell counts in mice (Fig. 2, Vehicle-Challenged vs S1P-Challenged groups; P<0.01).
S1P Neg (no) Regulation (effect) of Fig in lung
1) Confidence 0.19 Published 2010 Journal The Open Respiratory Medicine Journal Section Body Doc Link PMC3024555 Disease Relevance 0.61 Pain Relevance 0.16
The current study revealed that, although the S1P administration alone had no effect on the lung histology (Fig. 1A, B) and the BAL cell counts in control animals (Fig. 2, Vehicle-Control vs S1P-Control), administration of S1P prior to each antigen challenge aggravated the antigen-induced increase in BAL cell counts in mice (Fig. 2, Vehicle-Challenged vs S1P-Challenged groups; P<0.01).
S1P Neg (no) Regulation (effect) of Fig in lung
2) Confidence 0.19 Published 2010 Journal The Open Respiratory Medicine Journal Section Body Doc Link PMC3024555 Disease Relevance 0.61 Pain Relevance 0.16

General Comments

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