INT356372
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The loss of utrophin has no effect on the phenotype of mice in isolation, as dystrophin is the major structural protein of the muscle fibres. | |||||||||||||||
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Whereas it appears that dystrophin is able to fully compensate for the loss of utrophin in the single utrophin knockout mouse, the opposite is not true as there is significant dysfunction in the mdx even if it takes longer to become manifest, so utrophin is not able to fully compensate for the loss of dystrophin. | |||||||||||||||
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General Comments
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