INT356377

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.51 Pain Relevance 0

cytoplasm (Dmd, Mib2) endosome (Mib2) ligase activity (Mib2) signal transducer activity (Mib2) signal transduction (Mib2) nucleus (Dmd)

Dmd (Mus musculus) Mib2 (Mus musculus)

Pain Link Frequency Relevance Heat fibrosis 36 5.00 imagery 6 5.00 Inflammation 4 5.00 Calcium channel 2 5.00 cytokine 1 5.00 tolerance 1 5.00 Angina 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Muscular Dystrophy 140 99.84 Cardiomyopathy 63 95.08 Coronary Heart Disease 4 77.32 Fibrosis 43 5.00 Duchenne Muscular Dystrophy 20 5.00 Dilated Cardiomyopathy 18 5.00 Death 11 5.00 Stress 8 5.00 Congenital Anomalies 6 5.00 Myocardial Infarction 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The other major treatment option is to employ molecules that allow read-through of the stop codon in the dystrophin gene that causes the loss of the dystrophin protein in DMD.

dystrophin gene Positive_regulation (causes) of Negative_regulation (loss) of dystrophin protein associated with muscular dystrophy

1) Confidence 0.03 Published 2010 Journal The Open Cardiovascular Medicine Journal Section Body Doc Link PMC3024556 Disease Relevance 0.51 Pain Relevance 0

General Comments

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