INT3568

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Context Info
Confidence 0.62
First Reported 1975
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.27
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tf) mitochondrion (Tf) extracellular space (Tf)
extracellular region (Tf) cytoplasmic membrane-bounded vesicle (Tf)
Anatomy Link Frequency
hepatocyte 1
tail 1
Tf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 46 92.28 High High
Somatostatin 6 89.52 High High
Glutamate 9 87.20 High High
Potency 1 87.04 High High
Central nervous system 10 83.60 Quite High
agonist 36 80.12 Quite High
cytokine 1 73.28 Quite High
Morphine 1 68.80 Quite High
Pain 1 57.48 Quite High
Ziconotide 1 54.52 Quite High
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 2 97.86 Very High Very High Very High
Cancer 10 93.48 High High
Disease 8 83.96 Quite High
Stress 10 81.60 Quite High
Apoptosis 23 80.72 Quite High
Ovarian Cancer 1 65.60 Quite High
Schizophrenia 2 61.76 Quite High
Colon Cancer 6 60.72 Quite High
Aging 1 59.20 Quite High
Pain 1 57.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Structural analogs of TRF with low TSH-releasing activity did not inhibit GH release nor induced tail vibration in MS-treated rats.
Localization (releasing) of TRF in tail
1) Confidence 0.62 Published 1975 Journal Endocrinology Section Abstract Doc Link 810343 Disease Relevance 0 Pain Relevance 0.44
Under these culture conditions, albumin and transferrin secreted in vitro by adult rat hepatocyte spheroids were detectable by immunoprecipitation method at least until 2 months of culture.
Localization (secreted) of transferrin in hepatocyte
2) Confidence 0.50 Published 1992 Journal Exp. Cell Res. Section Abstract Doc Link 1572400 Disease Relevance 0 Pain Relevance 0.09
Once the iron is released from the Tfn, the Tfn-TfnR complex is recycled either directly or indirectly through the Golgi complex back to the cell surface [10].
Localization (released) of Tfn
3) Confidence 0.17 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2817924 Disease Relevance 0.71 Pain Relevance 0.11
For example, mRNAs for glutamic acid decarboxylase (GAD) 1, microtubule-associated protein tau, serpin A, malate dehydrogenase, regulator of G-protein signaling, transferrin, s100 calcium binding protein, glutathione-S-transferase, calmodulin, ?
Localization (glutathione-S-transferase) of transferrin associated with generalized anxiety disorder
4) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2924890 Disease Relevance 0.56 Pain Relevance 0.36

General Comments

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