INT35765

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Context Info
Confidence 0.56
First Reported 1988
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 47
Total Number 47
Disease Relevance 9.16
Pain Relevance 4.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (TXNRD1) small molecule metabolic process (TXNRD1) cytoplasm (TXNRD1)
cytosol (TXNRD1) signal transduction (TXNRD1) oxidoreductase activity (TXNRD1)
Anatomy Link Frequency
muscle 3
thyroid 2
TrA 2
cartridges 1
endothelial cell 1
TXNRD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tramadol 11 100.00 Very High Very High Very High
Paracetamol 12 99.90 Very High Very High Very High
backache 47 99.60 Very High Very High Very High
Angina 3 99.46 Very High Very High Very High
imagery 4 99.38 Very High Very High Very High
Pain 117 98.80 Very High Very High Very High
Inflammation 167 97.00 Very High Very High Very High
qutenza 34 96.00 Very High Very High Very High
metalloproteinase 3 94.08 High High
visual analogue scale 2 87.88 High High
Disease Link Frequency Relevance Heat
Mitral Valve Insufficiency 52 100.00 Very High Very High Very High
Aortic Valve Insufficiency 44 100.00 Very High Very High Very High
Tricuspid Valve Insufficiency 29 100.00 Very High Very High Very High
Low Back Pain 84 99.60 Very High Very High Very High
Cv General 3 Under Development 3 99.46 Very High Very High Very High
Pain 112 98.80 Very High Very High Very High
Stroke 208 97.80 Very High Very High Very High
INFLAMMATION 189 97.00 Very High Very High Very High
Epstein-barr Virus 141 97.00 Very High Very High Very High
Hypoxia 4 96.64 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Over the 6-month study period, does the TR group have greater improvement in disability (Disability component of the Late Life Function and Disability Instrument) [8] than a Usual Care group?


Gene_expression (group) of TR
1) Confidence 0.56 Published 2010 Journal Trials Section Body Doc Link PMC2904744 Disease Relevance 0.27 Pain Relevance 0
The primary research question is: Over the study period, does the TR group have greater improvement in function (motor sub-scale of the FONEFIM) than the Usual Care group?
Gene_expression (group) of TR
2) Confidence 0.56 Published 2010 Journal Trials Section Body Doc Link PMC2904744 Disease Relevance 0.11 Pain Relevance 0
Over the 6-month study period, does the TR group have greater improvement in physical function (motor subscale on the telephone version of the Functional Independence Measure [FONEFIM] [6,7] than a Usual Care group?


Gene_expression (group) of TR
3) Confidence 0.56 Published 2010 Journal Trials Section Body Doc Link PMC2904744 Disease Relevance 0.30 Pain Relevance 0
Over the 6-month study period, does the TR group have greater improvement in patient satisfaction (the Stroke Specific Patient Satisfaction with Care Scale) [10] than a Usual Care group?


Gene_expression (group) of TR associated with stroke
4) Confidence 0.56 Published 2010 Journal Trials Section Body Doc Link PMC2904744 Disease Relevance 0.22 Pain Relevance 0
FINDINGS: Twenty-eight studies, mostly including microvascular decompression (MVD) and radiofrequency thermorhizotomy (RF-TR), that met the inclusion criteria were included in the review.
Gene_expression (decompression) of RF-TR
5) Confidence 0.55 Published 2008 Journal Acta Neurochir (Wien) Section Body Doc Link 18193149 Disease Relevance 0 Pain Relevance 0
Most of the HP presented TR within the range reported in the literature, but two of them had higher values at T1.
Gene_expression (presented) of TR
6) Confidence 0.52 Published 2005 Journal Aviat Space Environ Med Section Body Doc Link 15945403 Disease Relevance 0.07 Pain Relevance 0
After purification and five-fold concentration of the sample (solid-phase extraction with Oasis MCX cartridges), the parent drug TR and its metabolites M1, M1G, M5 and M5G were easily detected, in comparison with standards, in an interference-free area of the electropherogram.
Gene_expression (detected) of TR in cartridges associated with tramadol
7) Confidence 0.52 Published 2004 Journal J Chromatogr A Section Abstract Doc Link 15281273 Disease Relevance 0 Pain Relevance 0.77
No difference between sides was found for the psoas and TrA muscles.
Gene_expression (muscles) of TrA in muscles
8) Confidence 0.47 Published 2008 Journal Br J Sports Med Section Body Doc Link 18065440 Disease Relevance 0.06 Pain Relevance 0
CONCLUSIONS: Individuals with unilateral lumbopelvic pain demonstrated a smaller increase in thickness of the TrA muscle during the ADIM.
Gene_expression (muscle) of TrA in TrA
9) Confidence 0.47 Published 2009 Journal J Orthop Sports Phys Ther Section Body Doc Link 19881003 Disease Relevance 0 Pain Relevance 0
For TrA activation, the binomial test was used.
Gene_expression (activation) of TrA
10) Confidence 0.46 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972594 Disease Relevance 0.39 Pain Relevance 0.24
Nevertheless, no associations between these reported symptoms and degree of AR, MR, or TR were seen at baseline in the population as a whole.
Gene_expression (degree) of TR associated with tricuspid valve insufficiency, mitral valve insufficiency and aortic valve insufficiency
11) Confidence 0.46 Published 2008 Journal BMC Med Section Body Doc Link PMC2585088 Disease Relevance 1.15 Pain Relevance 0.09
In each position, TrA thickness was measured (as an indirect measure of muscle activity) using ultrasound.
Gene_expression (thickness) of TrA in muscle
12) Confidence 0.41 Published 2009 Journal Man Ther Section Abstract Doc Link 19443261 Disease Relevance 0.24 Pain Relevance 0.24
Real-time ultrasound imaging was used to assess changes in thickness of the TrA and internal oblique IO muscles as well as lateral movement ("slide") of the anterior fascial insertion of the TrA muscle.
Gene_expression (thickness) of TrA in muscle associated with imagery
13) Confidence 0.41 Published 2009 Journal Eur Spine J Section Abstract Doc Link 19015895 Disease Relevance 0.64 Pain Relevance 0.73
No differences were observed for the TrA or IO muscles between the symptomatic and asymptomatic sides in those with (TrA, P = .263; IO, P = .172) or without (TrA, P = .780; IO, P = .635) lumbopelvic pain during the ADIM.
Gene_expression (muscles) of TrA in TrA
14) Confidence 0.41 Published 2009 Journal J Orthop Sports Phys Ther Section Body Doc Link 19881003 Disease Relevance 0 Pain Relevance 0
Cairms et al.31 found that individuals with a history of but no current low back pain had impairments in TrA contraction.
Gene_expression (contraction) of TrA associated with low back pain and backache
15) Confidence 0.40 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972594 Disease Relevance 0.76 Pain Relevance 0.65
A very similar oscillatory response appeared also in the total TFR, which we label TR I (total response I, t(15) = ?
Gene_expression (label) of TR I
16) Confidence 0.35 Published 2009 Journal Journal of pain research Section Body Doc Link PMC3004625 Disease Relevance 0.05 Pain Relevance 0.24
PR and TR were detected by their UV absorption at 220 nm.
Gene_expression (detected) of TR associated with paracetamol
17) Confidence 0.34 Published 2009 Journal J Chromatogr Sci Section Abstract Doc Link 19930793 Disease Relevance 0 Pain Relevance 0.59
RESULTS: Active TrPs were found in six patients (55%), whereas the remaining five patients showed latent TrPs.
Gene_expression (found) of TrPs
18) Confidence 0.34 Published 2008 Journal Am J Phys Med Rehabil Section Body Doc Link 18174844 Disease Relevance 0.07 Pain Relevance 0
The generation of TR?
Gene_expression (generation) of TR
19) Confidence 0.28 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2716050 Disease Relevance 0 Pain Relevance 0
The three-dimensional structure of the LBD domain is very well conserved amongst the thyroid hormone receptor (TR?
Gene_expression (conserved) of TR in thyroid
20) Confidence 0.24 Published 2010 Journal PPAR Research Section Body Doc Link PMC2825651 Disease Relevance 0.26 Pain Relevance 0.06

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