INT35866

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Context Info
Confidence 0.60
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 12
Disease Relevance 12.83
Pain Relevance 2.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
eosinophils 2
coronary artery 1
monocytes 1
dendritic cells 1
basophils 1
IGHE (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 3 100.00 Very High Very High Very High
Angina 9 99.04 Very High Very High Very High
Pain 5 93.04 High High
Inflammation 142 91.52 High High
Enkephalin 1 90.16 High High
Bile 1 88.92 High High
Cholecystokinin 1 88.40 High High
cytokine 78 86.64 High High
fibrosis 1 83.88 Quite High
Inflammatory marker 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Anaphylactic Hypersensitivity 1 99.60 Very High Very High Very High
Cv General 3 Under Development 11 99.04 Very High Very High Very High
Coronary Artery Disease 7 98.28 Very High Very High Very High
Anaphylaxis 34 96.44 Very High Very High Very High
Gastritis 4 95.64 Very High Very High Very High
Sclerosis 1 95.44 Very High Very High Very High
Drug Hypersensitivity 4 95.32 Very High Very High Very High
Urticaria 24 95.16 Very High Very High Very High
Ulcers 6 94.76 High High
Nasal Polyps 5 94.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In all the cases examined, the total serum IgE level was raised, specific serum IgE detectable and both the increased number of eosinophils and IgE-bearing cells found in biopsy specimens of gastric and/or duodenal tissues.
Transcription (raised) of IgE in eosinophils
1) Confidence 0.60 Published 1988 Journal Allergol Immunopathol (Madr) Section Abstract Doc Link 3228041 Disease Relevance 0.68 Pain Relevance 0.07
In all the cases examined, the total serum IgE level was raised, specific serum IgE detectable and both the increased number of eosinophils and IgE-bearing cells found in biopsy specimens of gastric and/or duodenal tissues.
Transcription (raised) of IgE in eosinophils
2) Confidence 0.60 Published 1988 Journal Allergol Immunopathol (Madr) Section Abstract Doc Link 3228041 Disease Relevance 0.68 Pain Relevance 0.07
Using a Pharmacia CAP system with a HHPA human serum albumin conjugate, specific IgE antibody was detected in serum from 1 (33.3%) out of the 3 workers.
Transcription (detected) of IgE
3) Confidence 0.53 Published 2001 Journal Ind Health Section Abstract Doc Link 11758999 Disease Relevance 0.62 Pain Relevance 0.09
In addition, transcripts of IgM, IgD, IgG1, IgG3, IgE, IgA, and the T cell receptor a gene were detected in single sperms.
Transcription (transcripts) of IgE in sperms
4) Confidence 0.50 Published 1998 Journal Mol. Gen. Genet. Section Abstract Doc Link 9645429 Disease Relevance 0.08 Pain Relevance 0.18
Omalizumab decreases free IgE levels rapidly and the expression of the high affinity IgE receptor expression on key effector cells, including mast cells, basophils, dendritic cells and monocytes.
Transcription (expression) of IgE in dendritic cells
5) Confidence 0.44 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 1.98 Pain Relevance 0.14
Omalizumab decreases free IgE levels rapidly and the expression of the high affinity IgE receptor expression on key effector cells, including mast cells, basophils, dendritic cells and monocytes.
Transcription (expression) of IgE in basophils
6) Confidence 0.15 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 1.98 Pain Relevance 0.14
Omalizumab decreases free IgE levels rapidly and the expression of the high affinity IgE receptor expression on key effector cells, including mast cells, basophils, dendritic cells and monocytes.
Transcription (expression) of IgE in monocytes
7) Confidence 0.15 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 1.98 Pain Relevance 0.14
Omalizumab decreases free IgE levels rapidly and the expression of the high affinity IgE receptor expression on key effector cells, including mast cells, basophils, dendritic cells and monocytes.
Transcription (expression) of IgE in mast cells
8) Confidence 0.15 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 1.98 Pain Relevance 0.14
Conclusion: This case describes IgE-mediated immediate hypersensitivity to chicken with cross-reactivity to turkey.
Transcription (describes) of IgE associated with anaphylactic hypersensitivity
9) Confidence 0.09 Published 2007 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2875553 Disease Relevance 1.14 Pain Relevance 0
No specific IgE antibodies to morphine were detected in any case.
Transcription (detected) of IgE associated with morphine
10) Confidence 0.06 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350147 Disease Relevance 0.47 Pain Relevance 0.33
Total IgE levels were significantly greater in the OVA + nano particle groups than in the vehicle group (P < 0.01 for OVA + 14 nm nano particle group, P < 0.05 for OVA + 56 nm nano particle group).
Transcription (levels) of IgE
11) Confidence 0.05 Published 2005 Journal Respir Res Section Body Doc Link PMC1242256 Disease Relevance 0 Pain Relevance 0
In unstable angina group the level of IL-1 beta was lower and the concentration of C-reactive protein, IgE was higher in comparison to group without coronary artery disease.
Transcription (concentration) of IgE in coronary artery associated with angina and coronary artery disease
12) Confidence 0.04 Published 2002 Journal Pol. Merkur. Lekarski Section Abstract Doc Link 12362502 Disease Relevance 1.08 Pain Relevance 0.89

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