INT3590

Context Info Confidence 0.40 First Reported 1976 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 7 Total Number 7 Disease Relevance 7.94 Pain Relevance 2.36

Anatomy Link Frequency sinus 1 anterior 1 posterior 1 left coronary artery 1 AVL9 (Homo sapiens)

Pain Link Frequency Relevance Heat depression 5 99.90 cva 58 98.48 ischemia 15 97.68 headache 8 97.56 Angina 20 96.84 abdominal pain 2 93.24 Pain 9 92.52 aspirin 2 64.16 nud 2 32.80 Calcium channel 2 32.00

Disease Link Frequency Relevance Heat Bundle-branch Block 9 99.90 Depression 5 99.90 Arrhythmias 2 Under Development 11 99.56 Pulmonary Embolism 33 99.28 Heart Rate Under Development 6 98.50 Coronary Artery Disease 11 98.12 Myocardial Infarction 29 98.10 Vomiting 2 97.84 Headache 6 97.56 Angina 14 96.84

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Repeat electrocardiogram with chest and limb leads reversed showed widespread, significant ST elevation in lead I, aVL, and V1 through V5 in keeping with extensive acute anterior myocardial infarction (MI).

Positive_regulation (elevation) of aVL in anterior associated with myocardial infarction

1) Confidence 0.40 Published 2005 Journal J Electrocardiol Section Abstract Doc Link 16216620 Disease Relevance 0.99 Pain Relevance 0.08

ST segment elevations in leads II, III, and aVF occurred intermittently with elevations in leads I and aVL, and with T wave flattening in V1, suggesting myocardial ischemia in areas supplied by the right coronary artery and by the circumflex branch of the left coronary artery.

Positive_regulation (elevations) of aVL in left coronary artery associated with coronary artery disease, ischemia and arrhythmias 2 under development

2) Confidence 0.34 Published 1976 Journal JAMA Section Abstract Doc Link 811819 Disease Relevance 0.73 Pain Relevance 0.41

Routine electrocardiography revealed monophasic ST-segment elevation in leads I and aVL and ST-segment depression in leads II, III, and aVF.

Positive_regulation (elevation) of aVL associated with depression

3) Confidence 0.34 Published 2001 Journal Neurol. Sci. Section Abstract Doc Link 11917978 Disease Relevance 1.17 Pain Relevance 0.63

The electrocardiogram (ECG) showed right bundle branch block, ST elevation in aVR, aVL and ST depression in all other leads.

Positive_regulation (elevation) of aVL associated with depression and bundle-branch block

4) Confidence 0.28 Published 1990 Journal Kokyu To Junkan Section Abstract Doc Link 2218092 Disease Relevance 0.90 Pain Relevance 0.24

An electrocardiogram showed ST segment elevation in leads I, aVL and V6 and hyperacute T wave changes in leads V3-V6 (figure 1).

Positive_regulation (elevation) of aVL associated with arrhythmias 2 under development

5) Confidence 0.19 Published 2001 Journal BMC Cardiovasc Disord Section Body Doc Link PMC60652 Disease Relevance 1.18 Pain Relevance 0.39

ECG showed changes suggestive of acute myocardial infarction - sinus tachycardia, ST elevations in V1-V3, S wave and ST depression in I, ST depression II, aVL, V5-V6 and ST elevation in aVR.

Positive_regulation (elevation) of aVL in sinus associated with heart rate under development, depression and myocardial infarction

6) Confidence 0.07 Published 2010 Journal Cardiovasc Ultrasound Section Body Doc Link PMC3002912 Disease Relevance 2.16 Pain Relevance 0.61

A 12-lead electrocardiogram (ECG) revealed ST elevation in Lead II, III, and aVF and reciprocal changes in I and aVL, as well ST elevation in the rV4 (arrow) and high degree atrioventricular (AV) block (Fig. 1), consistent with acute inferio-posterior wall myocardial infarction.

Positive_regulation (elevation) of aVL in posterior associated with myocardial infarction

7) Confidence 0.00 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2678699 Disease Relevance 0.82 Pain Relevance 0

General Comments

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