INT35927

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Context Info
Confidence 0.67
First Reported 1988
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.26

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signal transduction (NMU) extracellular region (NMU) response to stress (NMU)
Anatomy Link Frequency
BHK 2
NMU 1
gut 1
NMU (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 4 99.96 Very High Very High Very High
Pain 1 84.60 Quite High
tetrodotoxin 1 80.56 Quite High
Disease Link Frequency Relevance Heat
Pain 1 84.60 Quite High
Anxiety Disorder 1 82.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we report the overexpression of the human NmU(2)R in the methylotrophic yeast Pichia pastoris and baby hamster kidney (BHK) cells using the Semliki Forest virus (SFV) system.
Positive_regulation (overexpression) of Gene_expression (overexpression) of NmU in BHK
1) Confidence 0.67 Published 2007 Journal Int. J. Biochem. Cell Biol. Section Abstract Doc Link 17445746 Disease Relevance 0.17 Pain Relevance 0.13
The gut neuropeptide, neuromedin U octapeptide (NMU-8) produced transient elevations in short-circuit current (EC50 = 0.7 nmol/l) after its contraluminal administration to sheets of porcine distal jejunal mucosa in vitro.
Positive_regulation (elevations) of in gut Gene_expression (produced) of neuromedin U in NMU associated with neuropeptide
2) Confidence 0.49 Published 1988 Journal Eur. J. Pharmacol. Section Abstract Doc Link 3243329 Disease Relevance 0 Pain Relevance 0.13

General Comments

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