INT36201

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Context Info
Confidence 0.66
First Reported 1988
Last Reported 2010
Negated 3
Speculated 1
Reported most in Body
Documents 8
Total Number 10
Disease Relevance 9.18
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ETFA) mitochondrion (ETFA) small molecule metabolic process (ETFA)
oxidoreductase activity (ETFA)
Anatomy Link Frequency
globe 1
T-cell 1
ETFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 2 97.96 Very High Very High Very High
Pain 6 91.12 High High
Inflammation 3 76.12 Quite High
Angina 1 69.92 Quite High
abdominal pain 1 65.28 Quite High
dexamethasone 2 60.72 Quite High
palliative 1 57.40 Quite High
methotrexate 1 11.88 Low Low
colic 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 8 99.96 Very High Very High Very High
Cancer 30 99.86 Very High Very High Very High
Chordoma 9 99.86 Very High Very High Very High
Disease 47 98.88 Very High Very High Very High
Epstein-barr Virus 11 98.72 Very High Very High Very High
Pleural Solitary Fibrous Tumor 5 98.56 Very High Very High Very High
Gliosis 1 97.64 Very High Very High Very High
Lymphatic System Cancer 8 96.92 Very High Very High Very High
Ependymoma 4 96.56 Very High Very High Very High
Neurilemmoma 26 93.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As control cases, we also investigated expression of EMA and carbonic anhydrase II in an ocular globe with retinal gliosis and three cases of myxopapillary ependymoma of the cauda equina.
Spec (investigated) Gene_expression (expression) of EMA in globe associated with ependymoma and gliosis
1) Confidence 0.66 Published 2005 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 16160486 Disease Relevance 0.96 Pain Relevance 0.10
However, the cells were all negative for cytokeratin 7 and EMA.
Neg (negative) Gene_expression (negative) of EMA
2) Confidence 0.65 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2430707 Disease Relevance 1.28 Pain Relevance 0
On immunohistochemistry, tumor cells showed diffuse positivity with vimentin, CD34 and BCL2 along with cytoplasmic positivity for MIC2 (CD99), whereas cytokeratin, EMA, calretinin and HBME-1 were negative.
Neg (negative) Gene_expression (negative) of EMA associated with cancer
3) Confidence 0.57 Published 2010 Journal Indian J Pathol Microbiol Section Abstract Doc Link 20699522 Disease Relevance 1.30 Pain Relevance 0.07
The appearance of the EMA syndrome coincided with the fast worsening of the ophthalmopathy.
Gene_expression (appearance) of EMA associated with syndrome
4) Confidence 0.53 Published 2004 Journal Minerva Endocrinol. Section Abstract Doc Link 15257258 Disease Relevance 1.12 Pain Relevance 0.09
Large, frequently intrasinusoidal tumor cells expressed CD138, EMA, weakly IgA and kappa, but were negative for other B-cell markers, T-cell markers and CD30.
Gene_expression (expressed) of EMA in T-cell associated with cancer
5) Confidence 0.41 Published 2005 Journal Pol J Pathol Section Abstract Doc Link 15921012 Disease Relevance 1.12 Pain Relevance 0.07
Chordomas cells express epithelial differentiation antigens (low molecular weight cytokeratins, EMA, CAM 52, HFM 62, even CEA), Vimentin and S-100 Protein: this triple positivity allow differentiation between chordomas and numerous others tumors.
Gene_expression (express) of EMA associated with cancer and chordoma
6) Confidence 0.32 Published 1988 Journal Ann Pathol Section Abstract Doc Link 3293577 Disease Relevance 1.15 Pain Relevance 0.07
At immunohistochemistry, HRSCs expressed the following molecules: CD30+, CD43+, CD15+/-, CD3+/-; and were negative for EMA, ALK and CD20.
Neg (negative) Gene_expression (negative) of EMA
7) Confidence 0.30 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1208867 Disease Relevance 1.00 Pain Relevance 0.09
However, the exact mechanisms damaging the intestinal mucosa and the exact role of autoantibodies such as tTG and EMA antibodies in the pathogenesis of the disease remains unsolved.
Gene_expression (antibodies) of EMA associated with disease
8) Confidence 0.07 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1435993 Disease Relevance 0.94 Pain Relevance 0
Spot 6 (Rv3028c) is an electron transfer flavoprotein alpha subunit.
Gene_expression (transfer) of flavoprotein alpha subunit
9) Confidence 0.01 Published 2010 Journal Proteome Sci Section Body Doc Link PMC2998474 Disease Relevance 0.16 Pain Relevance 0
Probable electron transfer flavoprotein alpha-subunit (fixb) was also highly conserved in mycobacteria and other microbes.


Gene_expression (transfer) of flavoprotein alpha-subunit
10) Confidence 0.01 Published 2010 Journal Proteome Sci Section Body Doc Link PMC2998474 Disease Relevance 0.15 Pain Relevance 0.10

General Comments

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