INT36330

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Context Info
Confidence 0.32
First Reported 1987
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 4.42
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GOT1) small molecule metabolic process (GOT1) biosynthetic process (GOT1)
carbohydrate metabolic process (GOT1) cellular nitrogen compound metabolic process (GOT1) lysosome (GOT1)
Anatomy Link Frequency
Blood 2
GOT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 2 100.00 Very High Very High Very High
fibrosis 2 89.92 High High
corticosteroid 8 86.12 High High
Pain 1 85.40 High High
Percutaneous transluminal coronary angioplasty 1 84.72 Quite High
methotrexate 86 83.20 Quite High
Bile 1 80.00 Quite High
Leflunomide 2 76.56 Quite High
opioid receptor 2 76.16 Quite High
alcohol 2 75.84 Quite High
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 2 100.00 Very High Very High Very High
Liver Cancer 1 98.12 Very High Very High Very High
Increased Venous Pressure Under Development 3 95.92 Very High Very High Very High
Disease 21 93.00 High High
Hepatitis C Virus Infection 2 92.88 High High
Pulmonary Fibrosis 2 90.72 High High
Exanthema 3 90.16 High High
Myocardial Infarction 3 89.28 High High
Heart Rate Under Development 1 88.96 High High
Pulmonary Disease 2 88.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In humans, only a small increase in incidence of elevated levels of serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase seems to be present and is not clearly different from that of the control groups.
Positive_regulation (increase) of Positive_regulation (elevated) of transaminase
1) Confidence 0.32 Published 1987 Journal Am. J. Med. Section Abstract Doc Link 3318450 Disease Relevance 0.92 Pain Relevance 0.11
Blood chemistry showed elevated lactic dehydrogenase (413 U/l) but no elevation in creatine phosphokinase or glutamic-oxaloacetic transaminase.
Positive_regulation (elevated) of Neg (no) Positive_regulation (elevation) of glutamic-oxaloacetic transaminase in Blood associated with disorders of creatine metabolism
2) Confidence 0.27 Published 2001 Journal Ann. Hematol. Section Abstract Doc Link 11757728 Disease Relevance 0.72 Pain Relevance 0.13
Patients were excluded if they had functional class IV using SteinbrockerÂ’s criteria [10], aspartate transaminase (AST), alanine transaminase (ALT) and serum creatinine ?
Positive_regulation (using) of Positive_regulation (aspartate) of transaminase
3) Confidence 0.04 Published 2008 Journal Mod Rheumatol Section Body Doc Link PMC2638601 Disease Relevance 1.03 Pain Relevance 0.37
Patients were excluded if they had functional class IV using SteinbrockerÂ’s criteria [10], aspartate transaminase (AST), alanine transaminase (ALT) and serum creatinine ?
Positive_regulation (using) of Positive_regulation (alanine) of transaminase
4) Confidence 0.04 Published 2008 Journal Mod Rheumatol Section Body Doc Link PMC2638601 Disease Relevance 1.10 Pain Relevance 0.37
Naltrexone significantly reduced the elevation of serum glutamate-oxalacetate transaminase and glutamate-pyruvate transaminase (as index of hepatic function) induced by LPS.
Positive_regulation (elevation) of Positive_regulation (induced) of glutamate-oxalacetate transaminase associated with glutamate
5) Confidence 0.01 Published 2005 Journal J. Biomed. Sci. Section Abstract Doc Link 15917999 Disease Relevance 0.58 Pain Relevance 0.28

General Comments

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